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Eli Lilly multitargeted antifolate ly231514
Multitargeted Antifolate Ly231514, supplied by Eli Lilly, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multitargeted+antifolate+ly231514/pemetrexed+alimta+ly231514/10__1021_slash_acs__orglett__0c01227-124-12-15
Average 90 stars, based on 1 article reviews
multitargeted antifolate ly231514 - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Designing Homogeneous Copper-Free Sonogashira Reaction through a Prism of Pd–Pd Transmetalation
Article Snippet: As a part of our anticancer investigations, we have been interested in multitargeted antifolate LY231514 (Eli Lilly and Company), which is FDA approved for chemotherapy in combination with other platinum drugs.

Article Title: Phase I and Pharmacologic Study of Sequences of Gemcitabine and the Multitargeted Antifolate Agent in Patients With Advanced Solid Tumors
Article Snippet: Purpose: Multitargeted antifolate (MTA) is an investigational agent that, like gemcitabine, exhibits broad activity in solid tumors.. A phase I trial of MTA and gemcitabine was undertaken, based on the demonstration of preclinical cytotoxic synergy.. Patients and Methods: Thirty-five patients (group I) received 164 courses (median, four; range, one to 14 courses) of treatment of gemcitabine at doses of 1,000 and 1,250 mg/m2 on days 1 and 8 and MTA at doses of 200, 300, 400, 500, and 600 mg/m2, given 90 minutes after gemcitabine on day 1.

Article Title: Designing Homogeneous Copper-Free Sonogashira Reaction through a Prism of Pd–Pd Transmetalation
Article Snippet: As a part of our anticancer investigations,29 we have been interested in multitargeted antifolate LY231514 (Eli Lilly and Company), which is FDA approved for chemotherapy in combination with other platinum drugs.



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